Tag: HPA axis suppression

Opioids and Adrenal Insufficiency: A Rare but Life-Threatening Side Effect You Need to Know

Natala Menezes
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January 16
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Opioid-induced adrenal insufficiency is a rare but life-threatening side effect of long-term opioid use that suppresses cortisol production. Many patients go undiagnosed until a medical crisis occurs. Early testing and awareness can prevent fatal outcomes.